抗癌药物药物化学第二版 1849条(本栏目收费,不能显示细节,电话15274084725)
7. Bleomycins ......161 161
8. Enediyne antibiotics .....165 165
9. Tirapazamine .....171 171
10. Penclomedine ......172 172
11. Radiotherapy and radiosensitizers .....173 173
11.1. Radiotherapy ..... 173 173
11.1.1. External beam radiotherapy ...175 175
11.1.2. Brachytherapy (internal radiation therapy) ..175 175
11.1.3. Radioisotope therapy ....175 175
11.1.4. Neutron irradiation .....178 178
11.2. Drugs Used to improve the results of radiotherapy .. 179 179
11.2.1. Radiosensitizers ....179 179
2. Monofunctional intercalating agents .....276 276
2.1. Ellipticine and its analogs .... 276 276
2.2. Actinomycins ...... 279 279
2.3. Fused quinolines ..... 280 280
2.4. Naphthalimides and related compounds .... 281 281
2.5. Chartreusin, elsamicin A, and related compounds ... 281 281
6. Mitotic kinesin inhibitors ......386 386
References .......387 387
DRUGS THAT INHIBIT SIGNALING PATHWAYS FOR TUMOR CELL GROWTH AND PROLIFERATION...392 392
1. Introduction .....392 392
2. Oncogenes and signal transduction .....393 393
3. The role of protein kinases in cancer: signaling pathways related to kinases ..394 394
4. Inhibitors of tyrosine kinases ....402 402
4.1. Inhibitors of EGFR (HER-1) .... 403 403
4.1.1. Small-molecule EGFR inhibitors ...405 405
4.1.2. Monoclonal antibodies acting as inhibitors of EGFR ...409 409
4.2. Inhibitors of HER-2 .... 410 410
4.3. Inhibitors of HER-3 .... 411 411