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药物发现的新方法 872条(本栏目收费,不能显示细节,电话13136136841)
Silent gene clusters, 105
105
Simvastatin, 95, 96
95 96
SMAC. See Second mitochondrial activator of caspase (SMAC) Small-molecule modulation BILH434, 130
130
compound 21b, 129, 130
129 130
pyridopyrimidine 1 inhibitor, 130
130
Small-molecule stabilizers, 132–133
132 133
Soil bacteria carfilzomib, 98–99
98 99
fidaxomicin, 99–100
99 100
Soluble guanylate cyclase (sGC) stimulator,228–230
228 230
SPR. See Structure–potency relationships (SPR) Steroid adrenosterone, 115, 116
115 116
Steroid hormones, 7–8
7 8
Streptomyces orientalis, 96
96
Streptomyces roseosporus, 97
97
Structure–activity relationships (SAR),244–245, 247
244 245 247
Structure–potency relationships (SPR),244–245, 247
244 245 247
Survival and Ventricular Enlargement (SAVE)trial, 226
226
Synthetic epothilone analogue sagopilone, 98
98
Synthetic lethality, 33
33