药物发现的新方法 872条(本栏目收费,不能显示细节,电话15274084725)
Silent gene clusters, 105 105
SMAC. See Second mitochondrial activator of caspase (SMAC) Small-molecule modulation BILH434, 130 130
compound 21b, 129, 130 130
pyridopyrimidine 1 inhibitor, 130 130
Small-molecule stabilizers, 132–133 133
Soil bacteria carfilzomib, 98–99 99
Soluble guanylate cyclase (sGC) stimulator,228–230 230
SPR. See Structure–potency relationships (SPR) Steroid adrenosterone, 115, 116 116
Streptomyces orientalis, 96 96
Streptomyces roseosporus, 97 97
Structure–activity relationships (SAR),244–245, 247 247
Structure–potency relationships (SPR),244–245, 247 247
Survival and Ventricular Enlargement (SAVE)trial, 226 226
Synthetic epothilone analogue sagopilone, 98 98
Synthetic lethality, 33 33