药物发现的新方法 872条(本栏目收费,不能显示细节,电话15274084725)
small-molecule modulation BILH434, 130 130
compound 21b, 129, 130 130
pyridopyrimidine 1 inhibitor, 130 130
small-molecule stabilizers, 132–133 133
Protein tyrosine phosphatases (PTPs), 46–48 48
PTPs. See Protein tyrosine phosphatases (PTPs) Pulmonary arteries (PAs), 227, 228 228
Pulmonary hypertension (PH), 227–230 230
Pulmonary toxicity, 272–273 273
Pulmonary vascular resistance (PVR), 228 228
PVR. See Pulmonary vascular resistance (PVR) Pyridopyrimidine 1 inhibitor, 130 130
PBPK model, 316–319, 323, 324 324
plasma concentrations, 325 325
SEARCH study, 325–327 327
systems pharmacology, 316 316
academic and pharmaceutical research,changing landscape in-house and outsourced research,academic collaborations and consortia, 17–18 18