α-D-galactose 1-phosphate
IUPAC 名称
{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid
描述
α-d-galactose 1-phosphate, also known as alpha-D-galactopyranosyl phosphate or A-D-galactopyranose 1-phosphoric acid, is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. α-d-galactose 1-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). α-d-galactose 1-phosphate can be found in a number of food items such as kai-lan, cinnamon, macadamia nut (m. tetraphylla), and durian, which makes α-d-galactose 1-phosphate a potential biomarker for the consumption of these food products. α-d-galactose 1-phosphate can be found primarily in blood, as well as in human erythrocyte and red blood cell tissues. α-d-galactose 1-phosphate exists in all living species, ranging from bacteria to humans. In humans, α-d-galactose 1-phosphate is involved in few metabolic pathways, which include galactose metabolism, lactose synthesis, and nucleotide sugars metabolism. α-d-galactose 1-phosphate is also involved in several metabolic disorders, some of which include GLUT-1 deficiency syndrome, congenital disorder of glycosylation cdg-iid, galactosemia III, and galactosemia.
异构
OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O
InChI标识符
InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3+,4+,5-,6-/m1/s1
键
HXXFSFRBOHSIMQ-FPRJBGLDSA-N