描述
Carbamic acid, also known as carbamate or aminoformic acid, belongs to organic carbonic acids and derivatives class of compounds. Those are compounds comprising the organic carbonic acid or a derivative thereof. Carbamic acid is soluble (in water) and a weakly acidic compound (based on its pKa). Carbamic acid can be found in a number of food items such as purple laver, soy bean, other cereal product, and dock, which makes carbamic acid a potential biomarker for the consumption of these food products. Carbamic acid can be found primarily in human neuron and placenta tissues. Carbamic acid exists in all living organisms, ranging from bacteria to humans. Carbamic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Carbamic acid is the compound with the formula NH2COOH. The attachment of the acid group to a nitrogen or amine (instead of carbon) distinguishes it from carboxylic acid and an amide. Many derivatives and analogues of carbamic acid are known. They are generally unstable, reverting to the parent amine and carbon dioxide. The deprotonated anion (or conjugate base) of this functional group is a carbamate. Carbamic acid is a planar molecule . If the compound has been ingested, rapid gastric lavage should be performed using 5% sodium bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered the eyes, they should be washed with large quantities of isotonic saline or water. In serious cases, atropine and/or pralidoxime should be administered. Anti-cholinergic drugs work to counteract the effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in conjunction with pralidoxime or other pyridinium oximes (such as trimedoxime or obidoxime), though the use of '-oximes' has been found to be of no benefit, or possibly harmful, in at least two meta-analyses. Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally (T3DB).
InChI标识符
InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)