1-18:2-2-18:2-sn-glycerol-3-phosphocholine
IUPAC 名称
(2-{[(2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium
描述
1-18:2-2-18:2-sn-glycerol-3-phosphocholine, also known as dilinoleoylphosphatidylcholine or L-dilinoleoyllecithin, is a member of the class of compounds known as phosphatidylcholines. Phosphatidylcholines are glycerophosphocholines in which the two free -OH are attached to one fatty acid each through an ester linkage. Thus, 1-18:2-2-18:2-sn-glycerol-3-phosphocholine is considered to be a glycerophosphocholine lipid molecule. 1-18:2-2-18:2-sn-glycerol-3-phosphocholine is practically insoluble (in water) and a moderately acidic compound (based on its pKa). 1-18:2-2-18:2-sn-glycerol-3-phosphocholine can be found in a number of food items such as green bean, malabar spinach, peach, and swede, which makes 1-18:2-2-18:2-sn-glycerol-3-phosphocholine a potential biomarker for the consumption of these food products. 1-18:2-2-18:2-sn-glycerol-3-phosphocholine can be found primarily in blood, saliva, and urine, as well as throughout all human tissues. In humans, 1-18:2-2-18:2-sn-glycerol-3-phosphocholine is involved in a couple of metabolic pathways, which include phosphatidylcholine biosynthesis PC(18:2(9Z,12Z)/18:2(9Z,12Z)) and phosphatidylethanolamine biosynthesis PE(18:2(9Z,12Z)/18:2(9Z,12Z)).
异构
CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC[C@]([H])(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC
InChI标识符
InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1
键
FVXDQWZBHIXIEJ-LNDKUQBDSA-N