O-Phosphotyrosine
public_id
FDB023821
IUPAC 名称
(2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid
描述
O-Phosphotyrosine is a phosphorylated amino acid that occurs in a number of proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. Small amounts of free phosphotyrosine can be found in urine (PMID: 7693088). Levels of this amino acid appear to be elevated in mammalian urine during liver regeneration (PMID: 7516161). Phosphotyrosine is also able to induce platelet aggregation in vitro and it has been suggested that free phosphotyrosine in blood could be meaningful for in vivo platelet activation (PMID: 1282059). [HMDB]
CAS号
21820-51-9
异构
N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(O)=O
InChI标识符
InChI=1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1
DCWXELXMIBXGTH-QMMMGPOBSA-N
平均分子量
261.040223633
id
23984
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