3,3',4'5-Tetrahydroxystilbene
IUPAC 名称
4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
描述
3,3',4'5-Tetrahydroxystilbene (or Piceatannol) is a phenolic stilbenoid. It is a metabolite of resveratrol found in red wine. A viral protein-tyrosine kinase (LMP2A) implicated in leukemia, non-Hodgkin's lymphoma and other diseases associated with Epstein-Barr virus, was recently found to be blocked by picetannol in vitro (PMID 2590224). Therefore there is research interest in piceatannol as an anti-cancer and anti-EBV drug. Piceatannol can also act as an agonist for estrogen receptor alpha in human breast cancer cells (PMID: 16216908). [HMDB]
异构
OC1=CC(\C=C\C2=CC(O)=C(O)C=C2)=CC(O)=C1
InChI标识符
InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+
键
CDRPUGZCRXZLFL-OWOJBTEDSA-N