N1-Methyl-2-pyridone-5-carboxamide
IUPAC 名称
1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
描述
N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin. (PMID 12694300) [HMDB]
InChI标识符
InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)
键
JLQSXXWTCJPCBC-UHFFFAOYSA-N