public_id

FDB023173

IUPAC 名称

(2S)-2-amino-3-(1H-imidazol-5-yl)propan-1-ol

描述

L-Histidinol, a structural analogue of the essential amino acid L-histidine, enhances the toxicity of a variety of anticancer drugs for many tumor cells of animal origin. (PMID 8297120) L-histidinol inhibits human Myristoyl- CoA:protein-myristoyltransferase (hNMT) (an essential eukaryotic enzyme that catalyzes the cotranslational transfer of myristate to the NH2-terminal glycine residue of a number of important proteins of diverse function). (PMID 9778369) [HMDB]. L-Histidinol is found in many foods, some of which are chicory roots, yellow bell pepper, globe artichoke, and gram bean.

CAS号

4836-52-6

异构

N[C@H](CO)CC1=CN=CN1

InChI标识符

InChI=1S/C6H11N3O/c7-5(3-10)1-6-2-8-4-9-6/h2,4-5,10H,1,3,7H2,(H,8,9)/t5-/m0/s1

键

ZQISRDCJNBUVMM-YFKPBYRVSA-N

平均分子量

141.090211989

id

23336

含有化合物的食物

食物id	食物名称
445	American pokeweed
192	American cranberry
319	American butterfish
289	Amaranth
412	Alpine sweetvetch
148	Almond
288	Allspice
5	Allium
287	Alfalfa
928	Albizia gummifera
551	Alaska wild rhubarb
385	Alaska blueberry
577	Agave
285	Agar
198	Adzuki bean
1004	Acorn squash
283	Acorn
282	Acerola
281	Abiyuch
280	Abalone