14R,15S-EpETrE
public_id
FDB022946
IUPAC 名称
13-[(2R,3S)-3-pentyloxiran-2-yl]trideca-5,8,11-trienoic acid
描述
14R,15S-EpETrE is the dominant extracellular metabolite of epoxygenase products of arachidonic acid released from human luteinised granulosa cells. Epoxyeicosatrienoic acids (EpETrEs) have been reported recently having vasodilatory effects and a role of P-450-dependent arachidonic acid monooxygenase metabolites is suggested in vasoregulation. The physiological role of this compound has not been totally established, although in other tissues EpETrEs are mainly involved in hormone production and in the vascular and renal systems. Some studies have implicated epoxygenase metabolites of arachidonic acid in the control of steroidogenesis in luteinised granulosa cells. (PMID: 12749593, 12361727, 1650001) [HMDB]
CAS号
98103-48-1
异构
[H][C@@]1(CCCCC)O[C@]1([H])CC=CCC=CCC=CCCCC(O)=O
InChI标识符
InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)/t18-,19+/m0/s1
JBSCUHKPLGKXKH-RBUKOAKNSA-N
平均分子量
320.23514489
id
23109
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