4-Fumarylacetoacetic acid
IUPAC 名称
(2E)-4,6-dioxooct-2-enedioic acid
描述
Fumarylacetoacetate is an intermediate in the metabolism of tyrosine. Fumarylacetoacetate hydrolase (FAH) is an enzyme which catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. FAH is the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia [HMDB]. 4-Fumarylacetoacetic acid is found in many foods, some of which are sweet potato, fenugreek, narrowleaf cattail, and highbush blueberry.
异构
OC(=O)CC(=O)CC(=O)\C=C\C(O)=O
InChI标识符
InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+
键
GACSIVHAIFQKTC-OWOJBTEDSA-N