public_id

FDB022378

IUPAC 名称

(1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-5-(dimethylamino)pentan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-5-ol

描述

25-Azacholesterol has potent hypocholesterolemic activity. (PMID 14287266) It specifically inhibits cholesterol side-chain cleavage resulting in a decrease in steroid hormone production (PMID 5165491). Azasteroids may be membrane effectors which, in the case of mitochondria, lead to changes in adenosine triphosphate levels and(or) dehydrogenase activity. Their effects on sterol metabolism, therefore, may be of secondary consideration. (PMID 994744) 25-azacholesterol can induce a myotonic state in muscles. (PMID 5009506) [HMDB]

CAS号

1973-61-1

异构

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCN(C)C

InChI标识符

InChI=1S/C26H45NO/c1-18(7-6-16-27(4)5)22-10-11-23-21-9-8-19-17-20(28)12-14-25(19,2)24(21)13-15-26(22,23)3/h8,18,20-24,28H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26-/m1/s1

键

RZPPEFJMRVRCDD-XSLNCIIRSA-N

平均分子量

387.350115067

id

22541

含有化合物的食物

食物id	食物名称
430	Ostrich
353	Mule deer
595	Mountain hare
358	Mallard duck
383	Horse
378	Guinea hen
373	Greylag goose
451	European rabbit
365	Emu
364	Elk
549	Domestic pig
541	Domestic goat
535	Deer
624	Columbidae (Dove, Pigeon)
334	Chicken
506	Cattle (Beef, Veal)
316	Buffalo
303	Bison
542	Beefalo
590	Anatidae