3-Hydroxy-2-methyl-[S-(R,R)]-butanoic acid
IUPAC 名称
(2R,3R)-3-hydroxy-2-methylbutanoic acid
描述
3-Hydroxy-2-methyl-butanoic acid (HMBA)is a normal urinary metabolite involved in the isoleucine catabolism, as well as presumably b-oxidation of fatty acids and ketogenesis, excreted in abnormally high amounts in beta-ketothiolase deficiency. Differences in the enantiomeric ratio of HMBA may originate from the enantioselectivity of different enzyme systems (PMID 10755375) [HMDB]
异构
C[C@@H](O)[C@@H](C)C(O)=O
InChI标识符
InChI=1S/C5H10O3/c1-3(4(2)6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t3-,4-/m1/s1
键
VEXDRERIMPLZLU-QWWZWVQMSA-N