药物代谢和相互作用 121条(本栏目收费,不能显示细节,电话15274084725)
Pharmacokinetics and Toxicokinetics in Drug Discovery and Development
Pharmacokinetic Data Analysis and Modeling of ADME Processes
Physiologically Based Pharmacokinetic (PBPK) Modeling: Usefulness and Applications
Translational Drug Discovery Research: Integration of Medicinal Chemistry, Computational Modeling, Pharmacology, ADME, and Toxicology
ADME of Herbal Dietary Supplements
ADME of Cardiovascular Drugs
Disposition of Biological Therapeutics: Monoclonal Antibodies, Proteins, and Peptides
Influence of Changes in Physiology, Transporters, and Enzyme Expression on Disposition and Metabolism of Drugs during Pregnancy and Clinical Implications
When and How to Apply ADMET Principles to Drug Discovery and Development
Molecular Challenges in Front-Loading Toxicity Testing of Anticancer Drugs in Drug Discovery
Role of ADME Studies in Selecting Drug Candidates: Dependence of ADME Parameters on Physicochemical Properties
Effective Early Drug Development
Identification of Drug Metabolites
Drug Bioactivation and Oxidative Stress
Drug Metabolism in Drug Safety Evaluation
In Silico Models of Drug Metabolism and Drug Interactions
Methods for Determination of Enzyme Kinetics and Metabolic Rates
Utility of Molecular-Based In Vitro Assays in Metabolic Liability of Drug Candidates
Applications Using Caco-2 and TC7 Cells for Drug Metabolism Studies
In Vitro Liver Systems to Study Induction/Inhibition: Prediction of In Vivo Metabolism and Drug–Drug Interactions
Assessing the Hepatic Disposition and Toxicity of Xenobiotics Using Primary Hepatocytes
Monoclonal Antibody Analyses of Microsomal Human Drug Metabolism and Multifunctional Cytochrome P450
Precision-Cut Tissue Slices: A Suitable In Vitro System for the Study of the Induction of Drug-Metabolizing Enzyme Systems
The Impact of Solubility and Dissolution Assessment on Formulation Strategy and Implications for Oral Drug Disposition
Integrated Approaches to Blood–Brain Barrier
Why Do We Need In Vivo Models in Drug Metabolism?