当前位置：药药网 / 医药文献 /单克隆抗体应对最终药物的生产,配制,递送和稳定性方面的挑战(本栏目收费,不能显示细节,电话13136136841)
关键字：
类型：
下载页码(大于0,小于196)：
单克隆抗体应对最终药物的生产,配制,递送和稳定性方面的挑战 407条(本栏目收费,不能显示细节,电话13136136841)
silicone oil interactions with proteins and mAbs,155,156
155 156
viscous solutions delivery using,153,154
153 154
Primary structure,68,69
68 69
Protein aggregation,70,71
70 71
degradation routes in silico methods to assessing,105
105
mutants as result of performing mutations,184
184
Cys oxidation,59,60
59 60
free thiol generation,61
61
and mixed disulfides in mAbs,60,62
60 62
acid and base catalysis of,47
47
and Asp isomerization in mAbs,50,51
50 51
acid base mechanism,48,49
48 49
cyclic imide formation,49
49
X-ray crystal structure for mAb I Fab,49,50
49 50
Degradation routes in mAbs,45
45
chemical and physical protein degradation,46
46
chemical degradation,45,51
45 51
Delivery device technology development using delivery devices to deliver large volume mAb formulations,153
153
drug formulation in chloride-based formulations,158
158
injectors for SC delivery,155
155
interactions with stainless steel needles,157,159
157 159
filling of highly concentrated mAbs into,160
160
leachables impact from,157
157
problems with tungsten,159
159