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单克隆抗体应对最终药物的生产,配制,递送和稳定性方面的挑战 407条(本栏目收费,不能显示细节,电话13136136841)
oxidation mechanism,51,62
51 62
physical degradation,67,77
67 77
Stability-indicating assays development,103,105
103 105
Stainless steel needles,157,159
157 159
Standard capillary electrophoresis instrumentation,167
167
Static light scattering (SLS),136,172,174
136 172 174
Sterile water for injection (SWFI),178,181
178 181
Storage modulus (G′),169
169
Subcutaneous (SC),2,3,71
2 3 71
analytical tools for high-concentration formulation development,136
136
bioavailability of high-concentration mAb formulation,135,136
135 136
challenge of formulating,131,132
131 132
impact on delivery due to high viscosity,132,134
132 134
manufacturing impact of high-concentration SC formulations,134,135
134 135
infusion devices,153,155
153 155
Sugars as lyoprotectants,115,117
115 117
Surface plasmon resonance (SPR),29
29
Surface-active agents,110,111
110 111
Tangential flow filtration (TFF),134,135,139,140
134 135 139 140
Target product profile (TPP),1
1
Tert-Butylhydroperoxide (TBHP),54,56
54 56
Tertiary structure,68,69
68 69
Tissue plasminogen activator (tPA),20
20
Glass capillary viscometry,165,166
165 166
Hagen Poiseuille equation,132,167,168
132 167 168
Halozyme technology,148,150
148 150