药物稳定性 348条(本栏目收费,不能显示细节,电话13136136841)
6.1. Simplest Decomposition Modes of Pure Solids 148
The Solid to Solid + Gas Reaction 149 149
Tempcrature Dependence of the Solid to Solid + Gas Reaction 152 152
The Solid to Liquid + Gas Reaction 154 154
Topochemical Reactions 161 161
Diffusion Controlled Interactions 162 162
General Interactions in Dosage Forms 165 165
8.1. Tartaric acid and sodium bicarbonate 166 166
Incompatibility Prevention Techniqucs 171
PH of the Microenvironment 172
Interactions Involving a Liquid Phase 173 173
Cases of Interaction of a Liquid with a Poorly Soluble Drug 177 177
eactions via the Gas Phase 178 178
Pseudo-polymorphic Transformations 184 184
Polymorphic Transformations 184 184
16.l. Pseudo-polymorphic transformations. Dehydration kinetics of hydrats 185
Photolysis the Solid State 187 187
Predominant Reaction Orders 192
Kinetics in the Dry Versus Moist State 193
Types of Surface Moisture 194
The Leeson-Mattocks Model 195
Kinetically Unavailable (Bound) Water 199
Microenvironmental pH 199
Very Low Moisture Contents 200