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药物稳定性 348条(本栏目收费,不能显示细节,电话13136136841)
6.1. Simplest Decomposition Modes of Pure Solids
148
The Solid to Solid + Gas Reaction 149
149
Tempcrature Dependence of the Solid to Solid + Gas Reaction 152
152
The Solid to Liquid + Gas Reaction 154
154
Topochemical Reactions 161
161
Diffusion Controlled Interactions 162
162
General Interactions in Dosage Forms 165
165
8.1. Tartaric acid and sodium bicarbonate 166
166
Incompatibility Prevention Techniqucs
171
PH of the Microenvironment
172
Interactions Involving a Liquid Phase 173
173
Cases of Interaction of a Liquid with a Poorly Soluble Drug 177
177
eactions via the Gas Phase 178
178
Pseudo-polymorphic Transformations 184
184
Polymorphic Transformations 184
184
16.l. Pseudo-polymorphic transformations. Dehydration kinetics of hydrats
185
Photolysis the Solid State 187
187
Predominant Reaction Orders
192
Kinetics in the Dry Versus Moist State
193
Types of Surface Moisture
194
The Leeson-Mattocks Model
195
Kinetically Unavailable (Bound) Water
199
Microenvironmental pH
199
Very Low Moisture Contents
200