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 临床试验药物安全性 1506条(本栏目收费,不能显示细节,电话13136136841)
degree of certainty,229 229 
primary objective of the study,228 228 
treatment effect expected,229 229 
statistical methods for determining trial size,231 231 
statistical terms commonly used in sample size calculations,230 230 
superiority analysis versus non-inferiority analysis,223,226 223 226 
time to event variables,239,241 239 241 
two-tailed test,212,214 212 214 
writing a sample size section of a clinical study protocol,244,245 244 245 
omalizumab for,80 80 
Astrocytoma everolimus for,165 165 
treating,267 267 
Atherosclerosis C-reactive protein as biomarker,398,400 398 400 
Atomexetine,698 698 
package insert of,698,699 698 699 
Adalimumab,538 538 
Add-on design active control,59,60 59 60 
Adefovir,166 166 
Adjuvant therapy chronic drug administration,327 327 
metastasis risk reduction,326,327 326 327 
staging accuracy,327 327 
meanings of adjuvant,327,328 327 328 
Adverse drug reaction (ADR),70,71,79,104,105,108,136,162 70 71 79 104 105 108 136 162 
Adverse event (AE) abnormal laboratory values,493 494 493 494
adverse drug reaction,494 494 
anticipation in clinical study design,487 487 
cause-and-effect data from raw data,522,523 522 523 
anticipated versus unanticipated,500,502 500 502 
drug induction,495,496 495 496 
statistician considerations,496 496 
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