药物设计-基于结构和配体的方法 1741条(本栏目收费,不能显示细节,电话15274084725)
complementary biophysical screening,35 35
fragment x-ray screening in, 32,34–35 35
with fragment x-rays, 32, 34–35 35
for docking, 3–4, 99–100, 104–105 105
GLIDE program and, 3, 4–5 5
SGX FAST fragment-based structure-guided 0
aromatic bromine and, 32 32
biochemical assays for, 35 35
complementary biophysical screening,35 35
deliverable properties for, 32 32
fragment library design in, 31–32, 37 37
chemical diversity of, 33 33
Lipinski’s rules and, 31 31
fragment x-ray screening in, 32, 34–35 35