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靶点信息19(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Phosphopantetheine adenylyltransferase (PPAT)
TARGTYPE
Literature-reported target
SYNONYMS
Pantetheine-phosphate adenylyltransferase; Dephospho-CoA pyrophosphorylase; COASY
FUNCTION
Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
SEQUENCE
VAGSPKQPVRGYYRGAVGGTFDRLHNAHKVLLSVACILAQEQLVVGVADKDLLKSKLLPELLQPYTERVEHLSEFLVDIKPSLTFDVIPLLDPYGPAGSDPSLEFLVVSEETYRGGMAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYERPELPTCL
DRUGINFO
2-Methyl-2,4-Pentanediol
DRUGINFO
4'-Phosphopantetheine
DRUGINFO
Dephospho Coenzyme A
KEGGPATH
hsa00770:Pantothenate and CoA biosynthesis
KEGGPATH
hsa01100:Metabolic pathways
WIKIPATH
WP1857:Metabolism of water-soluble vitamins and cofactors
目标的蛋白质ID
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| UNIPROID |
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目标的序列数据
| 标题 | 内容 |
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| Phosphopantetheine adenylyltransferase (PPAT) |
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