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靶点信息16(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
S-adenosylmethionine synthase type-2 (MAT2A)
TARGTYPE
Clinical trial target
SYNONYMS
Methionine adenosyltransferase II; Methionine adenosyltransferase 2; MAT-II; MAT 2; AdoMet synthase 2
FUNCTION
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
PDBSTRUC
6G6R; 6FWB; 6FCD; 6FCB; 6FBP
BIOCLASS
AdoMet synthase family
SEQUENCE
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
KEGGPATH
hsa00270:Cysteine and methionine metabolism
KEGGPATH
hsa01100:Metabolic pathways
KEGGPATH
hsa01230:Biosynthesis of amino acids
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00270 |
|
| hsa01100 |
|
| hsa01230 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| S-adenosylmethionine synthase type-2 (MAT2A) |
|