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靶点信息22(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Vasoactive intestinal polypeptide receptor 1 (VIPR1)
TARGTYPE
Clinical trial target
SYNONYMS
Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor-1; Vasoactive intestinal peptide receptor 1; VPAC1; VPAC-1; VIPR1; VIP-R-1; Pituitary adenylate cyclase activating polypeptide type II receptor; PACAP-R-2; PACAP type II receptor
FUNCTION
This is a receptor for vip. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is vip = pacap-27 > pacap-38.
PDBSTRUC
5IB5; 5IB4; 5IB3; 5IB2; 5IB1
SEQUENCE
MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
DRUGINFO
Vasoactive intestinal peptide
KEGGPATH
hsa04080:Neuroactive ligand-receptor interaction
WIKIPATH
WP1824:GPCR downstream signaling
WIKIPATH
WP1825:GPCR ligand binding
WIKIPATH
WP334:GPCRs, Class B Secretin-like
WIKIPATH
WP706:SIDS Susceptibility Pathways
REACPATH
R-HSA-418555:G alpha (s) signalling events
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP706 |
|
| WP334 |
|
| WP1825 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Vasoactive intestinal polypeptide receptor 1 (VIPR1) |
|