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靶点信息

标题

内容

相关药物

状态

TARGETID

T66120

FORMERID

TTDR00676

UNIPROID

KDSB_ECOLI

TARGNAME

Bacterial Deoxy-manno-octulosonate cytidylyltransferase (Bact kdsB)

GENENAME

Bact kdsB

TARGTYPE

Clinical trial target

SYNONYMS

kdsB; CMP-KDO synthetase; CMP-2-keto-3-deoxyoctulosonic acid synthetase; CKS; 3-deoxy-D-manno-octulosonate cytidylytransferase

FUNCTION

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.

PDBSTRUC

3K8E; 3K8D; 1VH1

BIOCLASS

Kinase

ECNUMBER

EC 2.7.7.38

SEQUENCE

MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR

DRUGINFO

D03ZKM

UX-001

Phase 3

DRUGINFO

D0G7CG

Cmp-2-Keto-3-Deoxy-Octulosonic Acid

Investigative

DRUGINFO

D07XZT

Cytidine-5'-Diphosphate

Investigative

DRUGINFO

D0S2QZ

Cytidine-5'-Monophosphate

Investigative

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容

目标的蛋白质ID

标题	内容
TARGETID	T66120
UNIPROID	KDSB_ECOLI
TARGNAME	Bacterial Deoxy-manno-octulosonate cytidylyltransferase (Bact kdsB)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Bacterial Deoxy-manno-octulosonate cytidylyltransferase (Bact kdsB)	MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR

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