靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

TARGETID

T63934

FORMERID

TTDI01921

UNIPROID

IFNA2_HUMAN

TARGNAME

Interferon-alpha 2 (IFNA2)

GENENAME

IFNA2

TARGTYPE

Successful target

SYNONYMS

LeIF A; Interferon alphaA; Interferon alpha2; Interferon alpha-A; Interferon alpha-2; IFNalpha2; IFNA2C; IFNA2B; IFNA2A; IFN-alpha-2

FUNCTION

Produced by macrophages, IFN-alpha have antiviral activities.

PDBSTRUC

4Z5R; 4YPG; 3SE3; 3S9D; 2LMS

BIOCLASS

Cytokine: interferon

SEQUENCE

MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE

DRUGINFO

D0P0WV

Interferon Alfa-2b

Approved

DRUGINFO

D0Y8OK

Peginterferon alfa-2a

Approved

DRUGINFO

D08NWC

Peginterferon alfa-2b

Approved

DRUGINFO

D00TJX

Albinterferon alfa-2b

DRUGINFO

Hebergel

DRUGINFO

Interferon alpha 2a

DRUGINFO

P-1101

DRUGINFO

Instiladrin

DRUGINFO

Interferon alpha-2b

目标的 KEGG 通路数据

标题	内容
hsa04060	Cytokine-cytokine receptor interaction
hsa04140	Regulation of autophagy
hsa04151	PI3K-Akt signaling pathway
hsa04620	Toll-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04623	Cytosolic DNA-sensing pathway
hsa04630	Jak-STAT signaling pathway
hsa04650	Natural killer cell mediated cytotoxicity
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05162	Measles
hsa05164	Influenza A
hsa05168	Herpes simplex infection
hsa05320	Autoimmune thyroid disease

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP619	Type II interferon signaling (IFNG)
WP1835	Interferon alpha/beta signaling
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T63934
UNIPROID	IFNA2_HUMAN
TARGNAME	Interferon-alpha 2 (IFNA2)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Interferon-alpha 2 (IFNA2)	MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE

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