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靶点信息74(本栏目收费,不能显示细节,电话15274084725)
靶点信息
TARGNAME
Adenylate cyclase type 1 (ADCY1)
TARGTYPE
Successful target
SYNONYMS
Ca(2+)/calmodulin-activated adenylyl cyclase; Adenylyl cyclase 1; Adenylate cyclase type I; ATP pyrophosphate-lyase 1
FUNCTION
Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
BIOCLASS
Phosphorus-oxygen lyase
SEQUENCE
MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA
DRUGINFO
Adenosine monophosphate
KEGGPATH
hsa00230:Purine metabolism
KEGGPATH
hsa04015:Rap1 signaling pathway
KEGGPATH
hsa04020:Calcium signaling pathway
KEGGPATH
hsa04022:cGMP-PKG signaling pathway
KEGGPATH
hsa04024:cAMP signaling pathway
KEGGPATH
hsa04062:Chemokine signaling pathway
KEGGPATH
hsa04114:Oocyte meiosis
KEGGPATH
hsa04261:Adrenergic signaling in cardiomyocytes
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00230 |
|
| hsa04015 |
|
| hsa04020 |
|
| hsa04022 |
|
| hsa04024 |
|
| hsa04062 |
|
| hsa04114 |
|
| hsa04261 |
|
| hsa04270 |
|
| hsa04540 |
|
| hsa04611 |
|
| hsa04713 |
|
| hsa04720 |
|
| hsa04723 |
|
| hsa04724 |
|
| hsa04725 |
|
| hsa04727 |
|
| hsa04750 |
|
| hsa04911 |
|
| hsa04912 |
|
| hsa04913 |
|
| hsa04914 |
|
| hsa04915 |
|
| hsa04916 |
|
| hsa04918 |
|
| hsa04921 |
|
| hsa04923 |
|
| hsa04970 |
|
| hsa04971 |
|
| hsa04972 |
|
| hsa04976 |
|
| hsa05032 |
|
| hsa05142 |
|
| hsa05146 |
|
| hsa05166 |
|
| hsa05200 |
|
| hsa05414 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP666 |
|
| WP536 |
|
| WP35 |
|
| WP289 |
|
| WP2754 |
|
| WP2688 |
|
| WP2662 |
|
| WP1978 |
|
| WP1831 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Adenylate cyclase type 1 (ADCY1) |
|