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靶点信息17(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Sclerostin (SOST)
SYNONYMS
UNQ2976/PRO7455/PRO7476
FUNCTION
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
SEQUENCE
MQLPLALCLVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY
KEGGPATH
hsa04310:Wnt signaling pathway
REACPATH
R-HSA-201681:TCF dependent signaling in response to WNT
REACPATH
R-HSA-3772470:Negative regulation of TCF-dependent signaling by WNT ligand antagonists
NET_PATH
NetPath_26:TWEAK Signaling Pathway
目标的蛋白质ID
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