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靶点信息10(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
KRAS G12D mutant messenger RNA (KRAS mRNA)
TARGTYPE
Clinical trial target
SYNONYMS
K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras
FUNCTION
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
SEQUENCE
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| KRAS G12D mutant messenger RNA (KRAS mRNA) |
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