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靶点信息71(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Human immunodeficiency virus Protease (HIV PR)
TARGTYPE
Successful target
SYNONYMS
HIV Retropepsin; HIV PR
FUNCTION
Gag-Pol polyprotein: Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. At low concentration, the polyprotein would promote translation, whereas at high concentration, the polyprotein would encapsidate genomic RNA and then shut off translation.
PDBSTRUC
6OE3; 6HAK; 6ELI; 6DUH; 6DUG
SEQUENCE
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Human immunodeficiency virus Protease (HIV PR) |
|