当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息18(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin-21 (IL21)
TARGTYPE
Clinical trial target
SYNONYMS
Za11; Interleukin21; IL-21
FUNCTION
May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. Cytokine with immunoregulatory activity.
BIOCLASS
Cytokine: interleukin
SEQUENCE
MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04630:Jak-STAT signaling pathway
KEGGPATH
hsa05321:Inflammatory bowel disease (IBD)
WIKIPATH
WP2328:Allograft Rejection
PANTPATH
P00036:Interleukin signaling pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04630 |
|
| hsa05321 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Interleukin-21 (IL21) |
|