当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Lymphotoxin beta receptor (LTBR)
TARGTYPE
Clinical trial target
SYNONYMS
Tumor necrosis factor receptor type III; Tumor necrosis factor receptor superfamily member 3; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor C receptor; TNFRSF3; TNFR3; TNFR-III; TNFCR; TNF-RIII; Lymphotoxin-beta receptor; D12S370
FUNCTION
Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT.
BIOCLASS
Cytokine receptor
SEQUENCE
MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGATPSNRGPRNQFITHD
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04064:NF-kappa B signaling pathway
KEGGPATH
hsa04066:HIF-1 signaling pathway
KEGGPATH
hsa04672:Intestinal immune network for IgA production
KEGGPATH
hsa05166:HTLV-I infection
KEGGPATH
hsa05203:Viral carcinogenesis
REACPATH
R-HSA-5668541:TNFR2 non-canonical NF-kB pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04064 |
|
| hsa04066 |
|
| hsa04672 |
|
| hsa05166 |
|
| hsa05203 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Lymphotoxin beta receptor (LTBR) |
|