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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Porphobilinogen deaminase (HMBS)
TARGTYPE
Clinical trial target
SYNONYMS
Preuroporphyrinogen synthase; PBGD; Hydroxymethylbilane synthase; HMBS
FUNCTION
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
PDBSTRUC
5M7F; 5M6R; 3EQ1; 3ECR
BIOCLASS
Alkyl aryl transferase
SEQUENCE
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDAH
KEGGPATH
hsa00860:Porphyrin and chlorophyll metabolism
KEGGPATH
hsa01100:Metabolic pathways
WIKIPATH
WP1852:Metabolism of porphyrins
WIKIPATH
WP561:Heme Biosynthesis
WHIZPATH
PW000158:Porphyrin Metabolism
PANTPATH
P02746:Heme biosynthesis
BIOCPATH
PWY-5189:Tetrapyrrole biosynthesis
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Porphobilinogen deaminase (HMBS) |
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