靶点信息199(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Bacterial Fimbrin D-mannose adhesin (Bact FimH)
TARGTYPE
Clinical trial target
SYNONYMS
fimH; b4320; Type 1 fimbrin D-mannose specific adhesin; Protein FimH; JW4283
FUNCTION
Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae).
PDBSTRUC
6GTY; 6GTX; 6G2S; 6G2R; 6.00E+15
SEQUENCE
MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ
DRUGINFO
Alkyl mannoside derivative 1
DRUGINFO
Alkyl mannoside derivative 10
DRUGINFO
Alkyl mannoside derivative 11
DRUGINFO
Alkyl mannoside derivative 12
DRUGINFO
Alkyl mannoside derivative 2
DRUGINFO
Alkyl mannoside derivative 3
DRUGINFO
Alkyl mannoside derivative 4
DRUGINFO
Alkyl mannoside derivative 5
DRUGINFO
Alkyl mannoside derivative 6
DRUGINFO
Alkyl mannoside derivative 7
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Bacterial Fimbrin D-mannose adhesin (Bact FimH) |
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