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靶点信息19(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
PAI1_HUMAN; PAI2_HUMAN; IPSP_HUMAN
TARGNAME
Plasminogen activator inhibitor (PAI)
GENENAME
SERPINE1; SERPINB2; SERPINA5
TARGTYPE
Clinical trial target
FUNCTION
Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation offibrinolysis.
SEQUENCE
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
KEGGPATH
hsa04066:HIF-1 signaling pathway
KEGGPATH
hsa04115:p53 signaling pathway
KEGGPATH
hsa04390:Hippo signaling pathway
KEGGPATH
hsa04610:Complement and coagulation cascades
KEGGPATH
hsa05142:Chagas disease (American trypanosomiasis)
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04066 |
|
| hsa04115 |
|
| hsa04390 |
|
| hsa04610 |
|
| hsa05142 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Plasminogen activator inhibitor (PAI) |
|