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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGTYPE
Clinical trial target
SYNONYMS
GRPP; GLP2; GLP1; GLP-1
FUNCTION
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
PDBSTRUC
6EDS; 5YQZ; 5VAI; 5OTX; 5OTW
SEQUENCE
MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
KEGGPATH
hsa04024:cAMP signaling pathway
KEGGPATH
hsa04080:Neuroactive ligand-receptor interaction
KEGGPATH
hsa04714:Thermogenesis
KEGGPATH
hsa04911:Insulin secretion
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04024 |
|
| hsa04080 |
|
| hsa04714 |
|
| hsa04911 |
|
| hsa04922 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|