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靶点信息13(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Aquaporin-1 (AQP1)
TARGTYPE
Clinical trial target
SYNONYMS
Water channel protein for red blood cells and kidney proximal tubule; Urine water channel; CHIP28; Aquaporin-CHIP; AQP-1
FUNCTION
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
PDBSTRUC
4CSK; 1IH5; 1H6I; 1FQY
BIOCLASS
Major intrinsic protein
SEQUENCE
MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
目标的蛋白质ID
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