靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

TARGETID

T42048

FORMERID

TTDI02031

UNIPROID

BRD3_HUMAN

TARGNAME

Bromodomain-containing protein 3 (BRD3)

GENENAME

BRD3

TARGTYPE

Clinical trial target

SYNONYMS

RING3like protein; RING3L; RING3-like protein; KIAA0043

FUNCTION

Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets. Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors.

PDBSTRUC

6I7A; 6I68; 6I5P; 6I41; 6BGH

BIOCLASS

Bromodomain

SEQUENCE

MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE

DRUGINFO

D05ICT

ABBV-744

Phase 1

DRUGINFO

D03RPJ

PMID26924192-Compound-102

Patented

DRUGINFO

D05XXS

PMID26924192-Compound-103

Patented

DRUGINFO

D03NWT

PMID26924192-Compound-104

Patented

DRUGINFO

D0NN4U

PMID26924192-Compound-105

Patented

DRUGINFO

D0YM3G

Pyrrolo-pyrrolone derivative 1

DRUGINFO

GW841819X

DRUGINFO

I-BET151

DRUGINFO

PMID24000170C36

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容
WP3295	Chemical Compounds to monitor Proteins

目标的蛋白质ID

标题	内容
TARGETID	T42048
UNIPROID	BRD3_HUMAN
TARGNAME	Bromodomain-containing protein 3 (BRD3)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Bromodomain-containing protein 3 (BRD3)	MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE

标题

内容

Bromodomain-containing protein 3 (BRD3)

最新招商产品更多>>