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靶点信息112(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cholecystokinin receptor type A (CCKAR)
TARGTYPE
Clinical trial target
SYNONYMS
CCKAR; CCK-AR; CCK-A receptor
FUNCTION
Receptor forcholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
PDBSTRUC
1PB2; 1HZN; 1D6G
SEQUENCE
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04020 |
|
| hsa04080 |
|
| hsa04911 |
|
| hsa04972 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP455 |
|
| WP2664 |
|
| WP24 |
|
| WP1825 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Cholecystokinin receptor type A (CCKAR) |
|