TARGETID

T13491

FORMERID

TTDS00430

UNIPROID

S29A1_HUMAN

TARGNAME

Solute carrier family 29 member 1 (SLC29A1)

GENENAME

SLC29A1

TARGTYPE

Successful target

SYNONYMS

SLC29A1; Nucleoside transporter, es-type; Nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; ENT1

FUNCTION

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (nbmpr) and is sodium-independent.

SEQUENCE

MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRWLPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKKVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV

DRUGINFO

LIDOFLAZINE

DRUGINFO

[3H]nitrobenzylmercaptopurine ribonucleoside

DRUGINFO

6-(4-Nitro-benzylsulfanyl)-9-phenethyl-9H-purine

DRUGINFO

9-Benzyl-6-(4-nitro-benzylsulfanyl)-9H-purine

DRUGINFO

Dilazep

DRUGINFO

KF24345

DRUGINFO

N6-CYCLOPENTYLADENOSINE

DRUGINFO

NBTGR

DRUGINFO

Nitrobenzylthioinosine

DRUGINFO

S6-nitrobenzyl mercaptopurine riboside