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靶点信息22(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Syndecan-1 (SDC1)
TARGTYPE
Clinical trial target
SYNONYMS
SYND1; SDC; CD138
FUNCTION
Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
PDBSTRUC
6EJE; 4GVD; 4GVC
BIOCLASS
Peptide translocating syndecan
SEQUENCE
MRRAALWLWLCALALSLQPALPQIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHLASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
DRUGINFO
CD138 CAR T cells
DRUGINFO
CAR-T cells targeting CD138
INTEPATH
avb3_integrin_pathway:Integrins in angiogenesis
INTEPATH
integrin3_pathway:Beta3 integrin cell surface interactions
INTEPATH
integrin5_pathway:Beta5 beta6 beta7 and beta8 integrin cell surface interactions
目标的蛋白质ID
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