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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Vitamin K epoxide reductase complex 1 (VKORC1)
TARGTYPE
Successful target
SYNONYMS
Vitamin K1 2,3-epoxide reductase subunit 1; VKORC1; VKOR; UNQ308/PRO351; MSTP576; MSTP134
FUNCTION
Involved invitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
BIOCLASS
Short-chain dehydrogenases reductase
SEQUENCE
MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH
KEGGPATH
hsa00130:Ubiquinone and other terpenoid-quinone biosynthesis
WIKIPATH
WP2762:PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
WHIZPATH
PW000047:Vitamin K Metabolism
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Vitamin K epoxide reductase complex 1 (VKORC1) |
|