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靶点信息20(本栏目收费,不能显示细节,电话15274084725)
靶点信息
TARGNAME
Pituitary adenylate cyclase-activating 38 (PACAP-38)
TARGTYPE
Clinical trial target
SYNONYMS
Pituitary adenylate cyclase-activating polypeptide; PACAP38; PACAP27; PACAP-38; PACAP-27; PACAP; ADCYAP1
FUNCTION
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
PDBSTRUC
2JOD; 2D2P; 1GEA
SEQUENCE
HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK
KEGGPATH
hsa04911:Insulin secretion
WIKIPATH
WP1824:GPCR downstream signaling
WIKIPATH
WP1825:GPCR ligand binding
WIKIPATH
WP1873:NGF signalling via TRKA from the plasma membrane
WIKIPATH
WP706:SIDS Susceptibility Pathways
REACPATH
R-HSA-187024:NGF-independant TRKA activation
REACPATH
R-HSA-418555:G alpha (s) signalling events
REACPATH
R-HSA-420092:Glucagon-type ligand receptors
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP706 |
|
| WP1873 |
|
| WP1825 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Pituitary adenylate cyclase-activating 38 (PACAP-38) |
|