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靶点信息15(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Thymic stromal lymphopoietin (TSLP)
TARGTYPE
Clinical trial target
SYNONYMS
Thymic stromal lymphopoietin
FUNCTION
Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
PDBSTRUC
5J13; 5J12; 5J11
SEQUENCE
MFPFALLYVLSVSFRKIFILQLVGLVLTYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04630:Jak-STAT signaling pathway
WIKIPATH
WP2203:TSLP Signaling Pathway
目标的蛋白质ID
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UNIPROID |
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TARGNAME |
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TARGTYPE |
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目标的序列数据
标题 | 内容 |
Thymic stromal lymphopoietin (TSLP) |
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