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靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
FCG3A_HUMAN; FCG3B_HUMAN
TARGNAME
Immunoglobulin gamma Fc receptor III (FCGR3)
TARGTYPE
Successful target
SYNONYMS
Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; IGFR3; FcRIIIb; FcRIIIa; FcRIII; FcR-10; Fc-gamma RIII; FCGR3; FCG3; CD16
FUNCTION
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
SEQUENCE
MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK
KEGGPATH
hsa04145:Phagosome
KEGGPATH
hsa04380:Osteoclast differentiation
KEGGPATH
hsa04650:Natural killer cell mediated cytotoxicity
KEGGPATH
hsa04666:Fc gamma R-mediated phagocytosis
KEGGPATH
hsa05140:Leishmaniasis
KEGGPATH
hsa05150:Staphylococcus aureus infection
KEGGPATH
hsa05152:Tuberculosis
KEGGPATH
hsa05322:Systemic lupus erythematosus
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04145 |
|
| hsa04380 |
|
| hsa04650 |
|
| hsa04666 |
|
| hsa05140 |
|
| hsa05150 |
|
| hsa05152 |
|
| hsa05322 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Immunoglobulin gamma Fc receptor III (FCGR3) |
|