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靶点信息

标题

内容

相关药物

状态

TARGETID

T82075

FORMERID

TTDR00969

UNIPROID

FTSZ_WOLSP

TARGNAME

Bacterial Celldivision protein FtsZ (Bact ftsZ)

GENENAME

Bact ftsZ

TARGTYPE

Clinical trial target

SYNONYMS

FtsZprotein; FtsZ

FUNCTION

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.

BIOCLASS

Peptidase

SEQUENCE

MSIDLSLPELPILHPRITVVGVGGAGGNAVNNMIQSNLQGVNFVVANTDAQALEKSLCDKKIQLGINLTKGLGAGALPDVGKGAAEESIDEIMEHIKDSHMLFITAGMGGGTGTGAAPVIAKAAREARAAVKDRAPKEKKILTVGVVTKPFGFEGVRRMPIAELGLEELQKYVDTLIVIPNQNLFRIANEKTTFSDAFKLADNVLHIGIRGVTDLMVMPGLINLDFADIETVMSEMGKAMIGTGEAEGEDRAISAAEAAISNPLLDNVSMKGAQGILINITGGGDMTLFEVDAAANRVREEVDENANIIFGATFDQAMEGRVRVSVLATGIDGRNNKSETSPISQSEDSEKEKFKWPYSQSESTQDKTLETKPAEQVSEGAKWGSNIYDIPAYLRRKK

DRUGINFO

DVY5D9

TXA709

Phase 1

DRUGINFO

D0Q5XD

5'-Guanosine-Diphosphate-Monothiophosphate

Investigative

DRUGINFO

D0C7LS

Guanosine-5'-Diphosphate

Investigative

DRUGINFO

D0H2TZ

Phosphomethylphosphonic Acid Guanylate Ester

Investigative

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容

目标的蛋白质ID

标题	内容
TARGETID	T82075
UNIPROID	FTSZ_WOLSP
TARGNAME	Bacterial Celldivision protein FtsZ (Bact ftsZ)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Bacterial Celldivision protein FtsZ (Bact ftsZ)	MSIDLSLPELPILHPRITVVGVGGAGGNAVNNMIQSNLQGVNFVVANTDAQALEKSLCDKKIQLGINLTKGLGAGALPDVGKGAAEESIDEIMEHIKDSHMLFITAGMGGGTGTGAAPVIAKAAREARAAVKDRAPKEKKILTVGVVTKPFGFEGVRRMPIAELGLEELQKYVDTLIVIPNQNLFRIANEKTTFSDAFKLADNVLHIGIRGVTDLMVMPGLINLDFADIETVMSEMGKAMIGTGEAEGEDRAISAAEAAISNPLLDNVSMKGAQGILINITGGGDMTLFEVDAAANRVREEVDENANIIFGATFDQAMEGRVRVSVLATGIDGRNNKSETSPISQSEDSEKEKFKWPYSQSESTQDKTLETKPAEQVSEGAKWGSNIYDIPAYLRRKK

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