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靶点信息105(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Squalene synthetase (FDFT1)
TARGTYPE
Discontinued target
SYNONYMS
Squalene synthase; SS; SQS; Farnesyl-diphosphate farnesyltransferase; FPP:FPP farnesyltransferase
FUNCTION
Participates in the isoprenoid biosynthetic pathway, catalyzing a two-step reaction in which two identical molecules of farnesyl pyrophosphate (FPP) are converted into squalene, with the consumption of NADPH.
PDBSTRUC
3WSA; 3WEK; 3WEJ; 3WEI; 3WEH
BIOCLASS
Alkyl aryl transferase
SEQUENCE
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
DRUGINFO
Lapaquistat acetate
DRUGINFO
(Z)-3-[2-(9H-fluoren-2-yloxy)ethylidene]-quinuclidine hydrochloride 31
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00100 |
|
| hsa01100 |
|
| hsa01130 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP430 |
|
| WP2797 |
|
| WP2706 |
|
| WP1982 |
|
| WP197 |
|
| WP1795 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Squalene synthetase (FDFT1) |
|