靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP2775:Toll-Like Receptors Cascades

WIKIPATH

WP75:Toll-like receptor signaling pathway

REACPATH

R-HSA-140534:Ligand-dependent caspase activation

REACPATH

R-HSA-166016:Toll Like Receptor 4 (TLR4) Cascade

REACPATH

R-HSA-166058:MyD88:Mal cascade initiated on plasma membrane

REACPATH

R-HSA-166166:MyD88-independent TLR3/TLR4 cascade

REACPATH

R-HSA-2562578:TRIF-mediated programmed cell death

REACPATH

R-HSA-5602498:MyD88 deficiency (TLR2/4)

REACPATH

R-HSA-5603041:IRAK4 deficiency (TLR2/4)

REACPATH

R-HSA-936964:Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon

REACPATH

R-HSA-937041:IKK complex recruitment mediated by RIP1

REACPATH

R-HSA-937072:TRAF6 mediated induction of TAK1 complex

NET_PATH

NetPath_14:IL2 Signaling Pathway

NET_PATH

NetPath_16:IL4 Signaling Pathway

NET_PATH

NetPath_17:IL5 Signaling Pathway

INTEPATH

toll_endogenous_pathway:Endogenous TLR signaling

PANTPATH

P00054:Toll receptor signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04064	NF-kappa B signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04145	Phagosome
hsa04151	PI3K-Akt signaling pathway
hsa04620	Toll-like receptor signaling pathway
hsa05130	Pathogenic Escherichia coli infection
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05134	Legionellosis
hsa05140	Leishmaniasis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05144	Malaria
hsa05145	Toxoplasmosis
hsa05146	Amoebiasis
hsa05152	Tuberculosis
hsa05161	Hepatitis B
hsa05162	Measles
hsa05164	Influenza A
hsa05205	Proteoglycans in cancer
hsa05321	Inflammatory bowel disease (IBD)
hsa05323	Rheumatoid arthritis

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP2775	Toll-Like Receptors Cascades
WP2761	MyD88:Mal cascade initiated on plasma membrane
WP2752	MyD88-independent cascade
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS
WP2431	Spinal Cord Injury
WP2355	Corticotropin-releasing hormone
WP2272	Pathogenic Escherichia coli infection
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T81443
UNIPROID	TLR4_HUMAN
TARGNAME	Toll-like receptor 4 (TLR4)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Toll-like receptor 4 (TLR4)	MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI

标题

内容

Toll-like receptor 4 (TLR4)

最新招商产品更多>>