靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP2034:Leptin signaling pathway

WIKIPATH

WP2036:TWEAK Signaling Pathway

WIKIPATH

WP2112:IL17 signaling pathway

WIKIPATH

WP23:B Cell Receptor Signaling Pathway

WIKIPATH

WP231:TNF alpha Signaling Pathway

WIKIPATH

WP2324:AGE/RAGE pathway

WIKIPATH

WP2332:Interleukin-11 Signaling Pathway

WIKIPATH

WP2380:BDNF signaling pathway

WIKIPATH

WP2435:Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis

WIKIPATH

WP254:Apoptosis

WIKIPATH

WP2571:Polycystic Kidney Disease Pathway

WIKIPATH

WP262:EBV LMP1 signaling

WIKIPATH

WP2637:Structural Pathway of Interleukin 1 (IL-1)

WIKIPATH

WP2656:TAK1 activates NFkB by phosphorylation and activation of IKKs complex

WIKIPATH

WP2746:Signaling by the B Cell Receptor (BCR)

WIKIPATH

WP2752:MyD88-independent cascade

WIKIPATH

WP2759:Fc epsilon receptor (FCERI) signaling

WIKIPATH

WP2761:MyD88:Mal cascade initiated on plasma membrane

WIKIPATH

WP2763:Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

WIKIPATH

WP2768:MyD88 dependent cascade initiated on endosome

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04014	Ras signaling pathway
hsa04062	Chemokine signaling pathway
hsa04064	NF-kappa B signaling pathway
hsa04068	FoxO signaling pathway
hsa04150	mTOR signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04210	Apoptosis
hsa04380	Osteoclast differentiation
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04623	Cytosolic DNA-sensing pathway
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04910	Insulin signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa04930	Type II diabetes mellitus
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05206	MicroRNAs in cancer
hsa05212	Pancreatic cancer
hsa05215	Prostate cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05222	Small cell lung cancer

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP712	Estrogen signaling pathway
WP69	TCR Signaling Pathway
WP481	Insulin Signaling
WP395	IL-4 Signaling Pathway
WP382	MAPK Signaling Pathway
WP288	NLR Proteins
WP2804	Hair Follicle Development: Induction (Part 1 of 3)
WP2801	MyD88 cascade initiated on plasma membrane
WP2795	Cardiac Hypertrophic Response
WP2794	Cytosolic sensors of pathogen-associated DNA
WP2768	MyD88 dependent cascade initiated on endosome
WP2763	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
WP2761	MyD88:Mal cascade initiated on plasma membrane
WP2759	Fc epsilon receptor (FCERI) signaling
WP2752	MyD88-independent cascade
WP2746	Signaling by the B Cell Receptor (BCR)
WP2656	TAK1 activates NFkB by phosphorylation and activation of IKKs complex
WP2637	Structural Pathway of Interleukin 1 (IL-1)
WP262	EBV LMP1 signaling
WP2571	Polycystic Kidney Disease Pathway
WP254	Apoptosis
WP2435	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
WP2380	BDNF signaling pathway
WP2332	Interleukin-11 Signaling Pathway
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2112	IL17 signaling pathway
WP2036	TWEAK Signaling Pathway
WP2034	Leptin signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP1976	Signalling by NGF
WP195	IL-1 signaling pathway
WP1927	TCR signaling
WP1904	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
WP1839	Interleukin-1 signaling
WP1772	Apoptosis Modulation and Signaling
WP1584	Type II diabetes mellitus
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1449	Regulation of toll-like receptor signaling pathway
WP1434	Osteopontin Signaling
WP1433	NOD pathway

目标的蛋白质ID

标题	内容
TARGETID	T78429
UNIPROID	IKKB_HUMAN
TARGNAME	Inhibitor of nuclear factor kappa-B kinase beta (IKKB)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Inhibitor of nuclear factor kappa-B kinase beta (IKKB)	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS

标题

内容

Inhibitor of nuclear factor kappa-B kinase beta (IKKB)

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