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靶点信息38(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Antithrombin-III (ATIII)
TARGTYPE
Successful target
SYNONYMS
SERPINC1; ATIII; AT3
FUNCTION
Most important serine protease inhibitorin plasma that regulates the blood coagulation cascade. At-iii inhibits thrombin as well as factors ixa, xa and xia. Its inhibitory activity is greatly enhanced in the presence of heparin.
PDBSTRUC
4EB1; 3KCG; 3EVJ; 2ZNH; 2HIJ
SEQUENCE
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
DRUGINFO
Heparin low molecular weight
DRUGINFO
Unfractionated heparin
DRUGINFO
O-desulfated heparin
目标的蛋白质ID
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| UNIPROID |
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| TARGNAME |
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目标的序列数据
| 标题 | 内容 |
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| Antithrombin-III (ATIII) |
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